MCB Lab.
분자세포생물학연구실
Publications
90. Kim JH, Park YI, Hur M, Park WT, Koo SC, Her YC, Lee IS, Park J* (2022) The inhibitory activity of methoxyl flavonoids derived from Inula britannica flowers on SARS-CoV-2 3CLpro. International Journal of Biological Macromolecues in press.
89. Park R, Park YI, Park Y, Lee S, So J, Park J* (2022) CTRP1 Knockout Attenuates Tumor Progression in A549 and HCT116 Cancer Cells, Cancers 14184495
88. Kim JK, Bong SY, Park R, Park J, Jang DO (2022) An ESIPT-based fluorescent turn-on probe with isothiocyanate for detecting hydrogen sulfide in environmental and biological systems. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 278:121333
87. Kim H, Panda PK, Sadeghia K, Lee S, Chung C, Park Y, Park J, Seo J (2022) Facile thermal and hydrolytic conversion of tannic acid: Enhancement of antimicrobial activity and biocompatibility for biomedical applications. Materials Chemistry and Physics. 285:126141
86. Kitahata K, Uchida T, Taniguchi R, Kato A, Sugiura K, Sakakibara I, Oarada M, Fukawa T, Junsoo P, Inho C, Nikawa T. (2022) Additional effects of simultaneous treatment with C14-Cblin and celastrol on the clinorotation-induced rat L6 myotube atrophy.The Journal of Medical Investigation 69(1.2):127-134.
85. Nguyen QTT, Park HS, Lee TJ, Choi KM, Park JY, Kim D, Kim JH, Park J, Lee EJ. (2022) DKK3, Downregulated in Invasive Epithelial Ovarian Cancer, Is Associated with Chemoresistance and Enhanced Paclitaxel Susceptibility via Inhibition of the β-Catenin-P-Glycoprotein Signaling Pathway. Cancers 14(4):924.
84. Park J*, Park R, Jang M, Park YI, Park Y. (2022) Coronavirus enzyme inhibitors—experimentally proven natural compounds from plants. Journal of Microbiology, 60(3):347-354
83. Park R, Jang M, Park YI, Park Y, Jung W, Park J, Park J* (2021) EGCG, a green tea polyphenol, reduces coronavirus replication in a
mouse model. Viruses, 13(12), 2533
82. Jang M, Park R, Park YI, Park Y, Lee JI, Namkoong S, Lee EJ, Park J* (2021) LNX1 Contributes to Cell Cycle Progression and Cisplatin Resistance. Cancers, 13:3390
81. Park R, Jang M, Park YI, Park Y, Namkoong S, Lee JI, Park J* (2021) Elevated levels of CTRP1 in obesity contribute to tumor progression in a p53-dependent manner. Cancers, 13:3619.
80. Cha YE, Park R, Jang M, Park YI, Yamamoto A, Oh WK, Lee EJ, Park J* (2021) 6-Azauridine induces autophagy-mediated cell death via a p53- and AMPK-dependent pathway. Int J Mol Sci, 22:2947
79. Park J*, Park R, Jang M, Park YI (2021) Therapeutic potential of EGCG, a green tea polyphenol, for treatment of coronavirus diseases. Life, 11:197
78. Klionsky DJ,,,, Park J et al (2021) Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition). Autophagy. 17(1),1-382
77. Jang M, Park R, Park YI, Cha YE, Yamamoto A, Lee JI, Park J* (2021) EGCG, a green tea polyphenol, inhibits human coronavirus replication in vitro. Biochem Biophys Res Comm. 547:23-28
76. Lee EJ, Cho M, Rho SB, Park J, Chae DA, Nguyen QTT (2021) β-TrCP1-variant 4, a novel splice variant of β-TrCP1, is a negative regulator of β-TrCP1-variant 1 in β-catenin degradation. Biochem Biophys Res Comm. 542:9-16
75. Park K, Sadeghi K, Thanakkasaranee S, Park YI, Park J, Nam KH, Han H, Seo J. (2021) Effects of calcination temperature on morphological and crystallographic properties of oyster shell as biocidal agent. Int. J. Appl. Cer. Tech. 18(2):302-311
74. Kalichamy SS, Alcantara AV Jr, Kim BS, Park J, Yoon KH, Lee JI. (2020) Muscle and epidermal contributions of the structural protein β-spectrin promote hypergravity-induced motor neuron axon defects in C. elegans. Sci Rep. 10(1):21214.
73. Jang M, Park YI, Cha YE, Park R, Namkoong S, Lee JI, Park J*. (2020) Tea Polyphenols EGCG and Theaflavin Inhibit the Activity of SARS-CoV-2 3CL-Protease In Vitro. Evid Based Complement Alternat Med. 2020:5630838.
72. Park YI, Cha YE, Jang M, Park R, Namkoong S, Kwak J, Jang IS, Park J*. (2020) The Flower Extract of Abelmoschus manihot (Linn.) Increases Cyclin D1 Expression and Activates Cell Proliferation. J Microbiol Biotechnol. 30(7):1044-1050
71. Jo E, Jang HJ, Yang KE, Jang MS, Huh YH, Yoo HS, Park J, Jang IS, Park SJ (2020) Cordyceps militaris induces apoptosis in ovarian cancer cells through TNF-α/TNFR1-mediated inhibition of NF-κB phosphorylation. BMC Complement Med Ther 20(1):1
70. Jo E, Jang HJ, Yang KE, Jang MS, Huh YH , Yoo HS, Park J, Jang IS, Parkl SJ (2020) Cordyceps militaris exerts antitumor effects on carboplatin-resistant ovarian cancer via activation of ATF3/TP53 signaling in vitro and in vivo Natural Product Communications. 15(1) :1-14
69. Park R, Kim H, Jang M, Jo D, Park YI, Namkoong S, Lee JI, Jang IS, Park J* (2019) LNX1 contributes to tumor growth by downregulating p53 stability. FASEB J. 33(12):13216-13227
68. Li W, Cho MY, Lee S, Jang M, Park J, Park R (2019) CRISPR-Cas9 mediated CD133 knockout inhibits colon cancer invasion through reduced epithelial-mesenchymal transition. PLoS One. 14(8):e0220860
67. An JP, Ha TKQ, Kim HW, Ryu B, Kim J, Park J, Lee CH, Oh WK (2019) Eudesmane Glycosides from Ambrosia artemisiifolia (Common Ragweed) as Potential Neuroprotective Agents. J Nat Prod 82(5):1128-1138
66. Jo D, Park, R, KIm H, Jang M, Lee EJ, Jang IS, Park J* (2018) AMP-activated protein kinase regulates the expression of human telomerase reverse transcriptase. PLoS One. 13(11):e0207864
65. Jang M, Park R, Kim H, Namkoong S, Jo D, Huh YH, Jang IS, Lee JI, Park J *. (2018) AMPK contributes to autophagosome maturation and lysosomal fusion. Scientific Reports. 8(1) 12637
64. Kim H, Jang M, Park R, Jo D, Choi I, Choe J, Oh WK, Park J* (2018) Conessine treatment reduces dexamethasone-induced muscle atrophy by regulating MuRF1 and atrogin-1 expression. J Microbiol Biotechnol. 28(4) 520-526
63. Jang M, Kim H, Park R, Jo D, Lee EJ, Oh WK, Park J* (2017) 2,2’-methylenebis (6-tert-butyl 4-methylphenol) enhances the antitumor efficacy of belotecan, a derivative of camptothecin, by inducing autophagy. Oncotarget. 8(70) 115068-115078
62. Park R, Lee KI, Kim H, Jang M, Ha TKQ , Oh WK, Park J* (2017) Reserpine treatment activates AMP activated protein kinase (AMPK). Nat. Prod. Sci. 23(3):157-161
61. Seo JY, Pyo E, Park J, Kim JS, Sung SH, Oh WK. (2017) Nrf2-Mediated HO-1 Induction and Antineuroinflammatory Activities of Halleridone. J Med Chem. 20(11):1091-1099
60. Ju H, Kim T, Chung CM, Park J, Nikawa T, Park K, Choi I. (2017) Metabolic suppression by 3-iodothyronamine induced muscle cell atrophy via activation of FoxO-proteasome signaling and downregulation of Akt1-S6K signaling. Biol Pharm Bull 40(5) 576-582
59. Jafari N, Kim H, Park R, Li L, Jang M, Morris AJ, Park J*, Huang C* (2017) CRISPR-Cas9 mediated NOX4 knockout inhibits cell proliferation and invasion in HeLa Cells. PLoS One. 12(1): e0170327 (*:co-corresponding authors)
58. Kim SM, Kim H, Yang D, Park J, Park R, Namkoong S, Lee JI, Kim HS, Kim H*, Park J* (2017) An experimental and theoretical approach to optimize a three dimensional clinostat for life science experiments. Microgravity science and technology,29:97-106
57. Jang IS, Park JW, Jo EB, Cho CK, Lee YW, Yoo HS, Park J, Kim J, Jang BC, Choi JS. (2016) Growth inhibitory and apoptosis-inducing effects of allergen-free Rhus verniciflua Stokes extract on A549 human lung cancer cells. Oncol Rep. 36(5) 3047-3043
56. Kim H, Lee KI, Jang M, Namkoong S, Park R, Ju H, Choi I, Oh WK, Park J* (2016) Conessine Interferes with Oxidative Stress-Induced C2C12 Myoblast Cell Death through Inhibition of Autophagic Flux. PLoS One. 11(6):e0157096.
55. Hwang IH*, Park J*, Kim JM, Kim SI, Choi JS, Lee KB, Yun SH, Lee MG, Park SJ, Jang IS (2016) Tetraspanin-2 promotes glucotoxic apoptosis by regulating the JNK/β-catenin signaling pathway in human pancreatic β cells. FASEB J. 30(9):3107-16 (*; co-1st authors)
54. Yang JL, Quy Ha TK, Dhodary B, Seq JY, Kim H, Park J, Oh WK (2016) 3,4-seco-28-Nor-oleanane triterpenes from Camellia japonica protect from neurotoxicity in a rotenone model of Parkinson’s disease, Tetrahedron, 72(23) 3240-3249.
53. Klionsky DJ, Park J et al (2016) Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12:1-222.
52. Nguyen TM, Shin IW, Lee TJ, Park J, Kim JH, Park MS, Lee EJ. (2015) Loss of ITM2A, a novel tumor suppressor of ovarian cancer through G2/M cell cycle arrest, is a poor prognostic factor of epithelial ovarian cancer. Gynecol Oncol. 15:30210-9
51. Lee KI, Kim MJ, Koh H, Lee JI, Namkoong S, Oh WK, Park J* (2015) The anti-hypertensive drug Reserpine induces neuronal cell death through inhibition of autophagic flux. Biochem Biophys Res Comm 462:402-408
50. Namkoong S, Lee KI, Lee JI, Park R, Lee EJ, Jang IS, Park J* (2015) The integral membrane protein ITM2A, a transcriptional target of PKA-CREB, regulates autophagic flux via interaction with the vacuolar ATPase. Autophagy 11:756-768
49. Gwag T, Park K, Park J, Lee JH, Nikawa T, Choi I (2015) CELASTROL OVERCOMES HSP72 GENE SILENCING-MEDIATED MUSCLE ATROPHY AND INDUCES MYOFIBER PRESERVATION. J. Physiol Pharm 66:273-283
48. Park R, Hwang JY, Lee KI, Namkoong S, Choi SK, Park S, Park H, Park J* (2015) Measurement of antibodies to Varicella-zoster virus using a virus-free fluorescent-antibody-to-membrane antigen (FAMA) test. J Microbiol Biotechnol 25:268-73
47. Hwang JH, Sung JS, Kim JM, Chung YH, Park J, Lee SH, Jang IS (2014) Caveolin-1-dependent and -independent uPAR signaling pathways contribute to ganglioside GT1b induced early apoptosis in A549 lung cancer cells. Am J Cancer Res 19:801-10
46. Yang JL, Ha TK, Dhodary B, Kim KH, Park J, Lee CH, Kim YC, Oh WK (2014) Dammarane Triterpenes as Potential SIRT1 Activators from the Leaves of Panax ginseng. J Nat Prod 25:1615-1623
45. Ryu HW, Choi SH, Namkoong S, Jang IS, Seo DH, Choi I, Kim HS, Park J* (2014) Simulated microgravity contributes to autophagy induction by regulating AMP-activated protein kinase. DNA Cell Biol 33:128-135
44. Uma Maheswara Rao K, Namkoong S, Yu HC, Park J, Chung CM, Oh SY (2013) Green Synthesis and Biological Evaluation of New Di-α-aminophosphonate Derivatives as Cytotoxic Agents. Arch Pharm 346:851-859
43. Gwag T, Park K, Kim E, Son C, Park J, Nikawa T, Choi I (2013) Inhibition of C2C12 myotube atrophy by a novel HSP70 inducer, celastrol, via activation of Akt1 and ERK1/2 pathways. Arch Biochem Biophys 37:21-30
42. Ryu HW, Oh WK, Jang IS, Park J* (2013) Amurensin G induces autophagy and attenuates cellular toxicities in a rotenone model of Parkinson's disease. Biochem Biophys Res Comm 433:121-126
41. Shin JH, Min SH, Kim SJ, Kim YI, Park J, Lee HK, Yoo OJ (2013) TAK1 regulates autophagic cell death by suppressing the phosphorylation of p70 S6 kinase 1 Scientific Reports 3:srep01561
40. Lee H, Jang IS, Park J, Kim SH, Baek SY, Go SH, Lee SH (2013) Systemic immune modulation induced by alcoholic beverage intake in obese-diabetes (db/db) mice. Food Chem Toxciol 53:286-293
39. Ryu SW, Kim JH, Kim MK, Lee YJ, Park J, Park HM, Kim DH, Lee SH, Lee EJ (2013) Reduced expression of DKK3 is associated with adverse clinical outcomes of uterine cervical squamous cell carcinoma. Int J Gynecol Cancer 23:134-140
38. Hwang JW, Baek YM, Yang KE, Yoo HS, Cho CK, Lee YW, Park J, Eom CY, Lee ZW, Choi JS, Jang IS. (2013) Lactobacillus casei Extract Induces Apoptosis in Gastric Cancer by Inhibiting NF-κB and mTOR-Mediated Signaling. Integr Cancer Ther 12:165-173
37. Namkoong S, Lee EJ, Jang IS, Park J* (2012) Elevated level of Human RPA Interacting Protein α (hRIPα) in tumor cells is involved in cell proliferation through regulating RPA transport. FEBS Letters, 586:3753-3760
36. Yoon CH, Rho SB, Kim ST, Kho S, Park J, Jang IS, Woo S, Kim SS, Lee JH, Lee SH (2012) Crucial Role of TSC-22 in Preventing the Proteasomal Degradation of p53 in Cervical Cancer PLoS One 7:e42006
35. Kang WS, Cho SB, Park J, Lee MY, Mung SC, Kim WY, Lee SH, Kim DH, Lee EJ (2012) Clinico-epigenetic combination including quantitative methylation value of DKK3 augments survival prediction of the patient with cervical cancer J Cancer Res Clin Oncol, 139:97-106
34. Dao TT, Tran TL, Kim J, Nguyen PH, Lee EH, Park J, Jang IS, Oh Wk (2012) Terpenylated Coumarins As SIRT1 Activators Isolated from Ailanthus altissima J Nat Prod, 75:1332-1338
33. Klinosky D, Park J et al. (2012) Guidelines for the use and interpretation of assays for monitoring autophagy. Autophagy 4:445-544
32. Dao TT, Nguyen PH, Won HK, Kim EH, Park J, Won BY, Oh WK (2012) Curcuminoids from Curcuma longa and their inhibitory activities on influenza A neuraminidases. Food Chemistry 123:21-28
31. Hwang JW, Oh JH, Yoo HS, Lee YW, Cho CK, Kwon KR, Yoon JH, Park J, Her S, Lee ZW, Jang IS, Choi JS. (2012) Mountain ginseng extract exhibits anti-lung cancer activity by inhibiting the nuclear translocation of NF-κB. Am J Chin Med 40:187-202
30. Song MC, Park J, Kim TJ (2012) Diethylstilbestrol induces arrest of rat vascular smooth muscle cell cycle progression through downregulation of cyclin D1 and cyclin E. Mol Cell Biochem 360:103-109
29. Yoon JH, Her S, Kim M, Jang IS, Park J* (2012) The expression of damage-regulated autophagy modulator 2 (DRAM2) contributes to autophagy induction. Mol Biol Rep 39:1087-1093
28. Yang KE, Kwon J, Rhim JH, Choi JS, Kim SI, Lee SH, Park J*, Jang IS* (2011) Differential expression of extracellular matrix proteins in senescent and young human fibroblasts: a comparative proteomics and microarray study. Mol Cells 32:99-106 (*; co-corresponding authors)
27. Namkoong S, Kim TJ, Jang IS, Oh WK, Kang KW, Park J* (2011) Alpinumisoflavone induces apoptosis and suppresses ERK/MAPK and NF-κB pathways in lung tumor cells. Biol Pham Bull 34:203-208
26. Park K, Chung YJ, So H, Kim K, Park J, Oh M, Jo M,Choi K, Lee EJ, Choi YL, song SY, Bae DS, Kim BG, Lee JH (2011) AGR2, a mucinous ovarian cancer marker, promotes cell proliferation and migration. Exp Mol Med 43:91-100
25. Dao TT, Nguyen PH, Lee HS, Kim E, Park J, Lim SI, Oh WK (2011) Chalcones as novel influenza A (H1N1) neuraminidase inhibitors from Glycyrrhiza inflata. Bioorg Med Chem Lett. 21:294-298
24. Lee SE, Jang IS, Park J, Lee JH, Lee SY, Baek SY, Lee SH, Lee H (2010) Systemic immunity of obese-diabetes model (db/db) mice. Mol Cell. Toxicol 6:143-149
23. Nguyen TNA, Dao TT, Tung BT, Choi H, Kim E, Park J, Lim SI, Oh WK (2010) Influenza A (H1N1) Neuraminidase Inhibitors from Vitis amurensis. Food Chem. 124:437-443
22. Jong JE *, Park J*, Kim S, Seo T. (2010) Kaposi's sarcoma-associated herpesvirus viral protein kinase interacts with RNA helicase a and regulates host gene expression. J Microbiol 48:206-212 (*; co-1st authors)
21. Cha S, Lim C, Lee JY, Song YJ, Park J, Choe J, Seo T. (2010) DNA-PK/Ku complex binds to latency-associated nuclear antigen and negatively regulates Kaposi's sarcoma-associated herpesvirus latent replication. Biochem Biophys Res Comm. 394:934-939
20. Park SM, Chae M, Kim BK, Seo T, Jang IS, Choi JS, Kim IC, Lee JH, Park J*. (2010) SUMOylated IRF-1 shows oncogenic potential by mimicking IRF-2. Biochem Biophys Res Comm. 391:926-930
19. Park SM, Kim K, Lee EJ, Kim BK, Lee TJ, Seo T, Jang IS, Lee SH, Kim S, Lee JH, Park J*. (2009) Reduced expression of DRAM2/TMEM77 in tumor cells interferes with cell death. Biochem Biophys Res Comm. 390:13401-13444
18. Chae M, Rhee GS, Jang IS, Kim K, Lee JH, Lee SY, Kim M, Yang J, Park J*, Lee SH*. (2009) ATG5 expression induced by MDMA (ecstasy), interferes with neuronal differentiation of neuroblastoma cells. Mol. Cells. 27:571-575 (*; co-corresponding authors)
17. Lee EJ, Jo M, Rho SB, Park K, Yoo YN, Park J, Chae M, Zhang W, Lee JH. (2009) Dkk3, down-regulated in cervical cancer, functions as a negative regulator of beta-catenin. Int. J. Cancer. 124:287-297
16. Kim K1, Lee EJ, Lee SH, Seo T, Jang IS, Park J, Lee JH (2009) Species-specific variation of RPA-interacting protein (RIP) splice isoforms. BMB Rep 42:22-7
15. Chae M, Kim K, Park SM, Jang IS, Seo T, Kim DM, Kim IC, Lee JH and Park J*. (2008) Interferon Regulatory Factor-2 (IRF-2) regulates NF-kB activity by modulating the subcellular localization of NF-kB. Biochem Biophys Res Comm. 380:519-524
14. Park J, Lee MS, Yoo SM, and Seo T. (2008) A Novel Protein Encoded by Kaposi's Sarcoma-Associated Herpesvirus Open Reading Frame 36 Inhibits Cell Spreading and Focal Adhesion Kinase Activation. Intervirology. 50:426-432
13. Park J, Kim K, Lee EJ, Seo YJ, Lim SN, Park K, Rho SB, Lee SH, and Lee JH. (2007) Elevated Level of SUMOylated IRF-1 in Tumor Cells Interferes with IRF-1 Mediated Apoptosis. Proc. Natl. Acad. Sci. USA. 104:17028-17033.
12. Park J*, Lee MS, Yoo SM, Jeong KW, Lee D, Choe J, and Seo T*. (2007) Identification of the DNA Sequence Interacting with Kaposi's Sarcoma-Associated Herpesvirus Viral Interferon Regulatory Factor 1. Journal of Virology 81:12680-12684. (*; co-corresponding authors)
11. Lee EJ, Jo M, Park J, Zhang W, Rho SB, and Lee JH. (2006) Alternative splicing variants of IRF-1 lacking exons 7, 8, and 9 in cervical cancer. Biochem Biophys Res Comm. 347:882-888.
10. Park J, Seo T, Kim H, and Choe J. (2005) Sumoylation of a novel protein hRIPbeta is involved in RPA deposition in PML nuclear body. Mol. Cell. Biol. 25:8202-8214.
9. Seo T, Park J and Choe J. (2005) Viral interferon regulatory factor 1 of Kaposi's Sarcoma-associated herpesvirus inhibits transforming growth factor-b signaling. Cancer Res. 65:1738-1747.
8. Park J, Seo T, Jung J, and Choe J. (2004) Herpesvirus Saimiri STP A11 Protein Interacts with STAT3 and Stimulates its Transcriptional Activity. Biochem Biophys Res Comm. 320:274~280.
7. Seo T, Park J, Lim C, and Choe J. (2004) Inhibition of Nuclear Factor kappaB Activity by Viral Interferon Regulatory Factor 3 of Kaposi's Sarcoma-Associated Herpesvirus. Oncogene. 23:6146-6155.
6. Park J, Cho N, Choi JK, Feng P, Choe J, and Jung JU. (2003) Distinct Roles of Cellular Lck and p80 Proteins in Herpesvirus Saimiri Tip function on Lipid Rafts. Journal of Virology 77:9041-9051.
5. Feng P, Park J, Lee B, Lee S, Bram RJ, and Jung JU. (2002) Kaposi's Sarcoma-Associated Herpesvirus Mitochondrial K7 protein targets a cellular calcium-modulating cyclophin ligand to modulate intracellular calcium concentration and inhibit apoptosis. Journal of Virology 76: 11491-11504.
4. Park J, Lee B, Choi JK, Means R, Choe J, and Jung JU. (2002) Herpesviral protein targets a novel cellular WD repeat endosomal protein to downregulate T lymphocyte receptor expression. Immunity. 17: 221-233.
3. Seo T, Park J, Lee D, Hwang SG, and Choe J. (2001) The viral interferon regulatory factor 1 of Kaposi's sarcoma-associated herpesvirus binds to p53 and represses p53-dependent transcription and apoptosis. Journal of Virology 75:6193-6198.
2. Park J, Seo T, Hwang S, Lee D, Gwack Y. and Choe J. (2000) The K-bZIP Protein from Kaposi's Sarcoma-Associated Herpesvirus Interacts with p53 and Represses Its Transcriptional activity. Journal of Virology 74:11977-11982.
1. Park J, Lee D, Seo T, Chung J, and Choe J. (2000) Kaposi's Sarcoma-Associated Herpesvirus (Human Herpesvirus 8) Open Reading Frame 36 protein is a Serine Protein Kinase. J. Gen. Virol. 81:1067-1071.